THE experts in the United States claims to have successfully developed a super immune cells that may help block cancer development in a group of patients who become objects of research.
As published online edition of the journal Nature Medicine, researchers from Baylor College of Medicine in Houston to create these immune cells by adding an artificial receptor (artificial) on T lymphocytes and enhance their ability to fight a deadly form of cancer called neuroblastoma.
Neuroblastoma damage the body by attacking the nervous system. Although relatively rare, this type of cancer is the cause of about seven percent of cases of cancer in children and 15 percent of non-adult cancer deaths. Approximately two-thirds of cases of this type of cancer diagnosis and often can not be found already spread to several parts of the body organs.
Naturally, T lymphocytes can not survive that long as well as loss of molecules that act against cancer cells in tumors. To overcome these two shortcomings, the research team led by Malcolm Brenner of Baylor College of Medicine Texas developed immune cells, called cell super-charge.
Tues super was developed from the immune cells that are naturally stimulated or dirangang by a virus that is harmless so-called Epstein-Barr virus. Experts modifying these cells to create a key receptor type of protein found in human neuroblastoma cells.
From the results of a study of 11 patients with neuroblastoma aged 3 to 10 years, cells engineered kekabalan is able to survive up to 18 months. In five cases, the tumor showed regression and sixth cases even completely healed.
"For the first time, we began to see a response to the tumor. We have seen the perfect remission in one case, while the other stable disease for a year, "he said.
For future research, Brenner and his team plan to add a receptor to other types of cancer cells to see if it also raises the same effects in facing cancer.
As published online edition of the journal Nature Medicine, researchers from Baylor College of Medicine in Houston to create these immune cells by adding an artificial receptor (artificial) on T lymphocytes and enhance their ability to fight a deadly form of cancer called neuroblastoma.
Neuroblastoma damage the body by attacking the nervous system. Although relatively rare, this type of cancer is the cause of about seven percent of cases of cancer in children and 15 percent of non-adult cancer deaths. Approximately two-thirds of cases of this type of cancer diagnosis and often can not be found already spread to several parts of the body organs.
Naturally, T lymphocytes can not survive that long as well as loss of molecules that act against cancer cells in tumors. To overcome these two shortcomings, the research team led by Malcolm Brenner of Baylor College of Medicine Texas developed immune cells, called cell super-charge.
Tues super was developed from the immune cells that are naturally stimulated or dirangang by a virus that is harmless so-called Epstein-Barr virus. Experts modifying these cells to create a key receptor type of protein found in human neuroblastoma cells.
From the results of a study of 11 patients with neuroblastoma aged 3 to 10 years, cells engineered kekabalan is able to survive up to 18 months. In five cases, the tumor showed regression and sixth cases even completely healed.
"For the first time, we began to see a response to the tumor. We have seen the perfect remission in one case, while the other stable disease for a year, "he said.
For future research, Brenner and his team plan to add a receptor to other types of cancer cells to see if it also raises the same effects in facing cancer.
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